Seeking Health Active B12 Lozenge with L-5-MTHF

Questions on Seeking Health Active B12 Lozenge with L-5-MTHF

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• Do you recommend taking both the sublingual B12/Metafolin and the Homocyste X 60 together? at 12/25/11 11:02 PM
  • I have 2 copies MTHFR C677T; severe chronic insomnia, depression, Hashimoto's, and unable to stop using benzodizepine for sleep. The pharmaceutical "Deplin" is 15MG of l-methylfolate. Is there any difference between Deplim (not over the counter) and these besides the dosage of these products which is much less. What do you suggest taking as a daily dosage and should both of these products be taken together? Have you had experience with insomnia being alleviated?
    
    Thanks,
    
    Susan
  • Hi Susan - I do not recommend taking these two together unless your doctor prescribes these amounts. Taking too much of a good thing is not good. Each person is different and the amounts taken vary immensely from person to person. I have had lots of experience alleviating insomnia. It is not that difficult to do - amazingly enough. It requires dietary changes, nutrients and lifestyle changes. Those with MTHFR make it more challenging but still possible - quite so. A consult is very much recommended here as there are too many factors at play here and a lot of education is needed. http://www.healthegoods.com/consult.html Best Dr Ben
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• DOSAGE FOR CHILDREN at 12/31/11 10:32 AM
  • I purchased a lot of Sublingual Active B12 with Metafolin to give to my parents, sibs, children, grandchildren and friends. We have a lot of 677TT in our family. Until we get everyone tested I am giving the same thing to everybody.
    
    Our youngest child is 5 years old and they get older. Is one of these tablets a day too much for children? Should I cut them in half, or give them every other day?
  • Hello - For the younger children, I highly recommend that you break them in half and give it to them every other day for now. See how they do on that amount. If they begin to show signs of agitation or irritability, then reduce the amount to a quarter tablet and give every other day. If they show improvement on 1/2 tablet every other day, try giving every day. It is best to start very low and then work up. Excellent question. Best Dr Ben
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• DOSAGE FOR CHILDREN at 1/3/12 7:41 PM
  • I understand the dosage. Thank you. It is a very pleasant experience to take these sweet tiny sublingual tablets!
    
    I am concerned that you said to watch for agitation or irritability. We never worried about that with multivitamins. I thought you couldn't get too much of these two vitamins.
    
    Which can there be too much of? The Methylfolate or the Methylcobalamin?
    
    If the Methylcobalamin of concern. And if it is the only component that is sublingual, would it be better for children to swallow the tablet and absorb less Methylcobalamin?
    
    Thanks!
  • Hello - It is the methylfolate - not the methylcobalamin - that may cause the agitation. With MTHFR mutations, the ability for the body to make active methylfolate is significantly reduced. This is why these tiny sweet tasting tablets are necessary ;) However, too much of a good thing is not good either. Multivitamins can also cause issues if they are a quality multivitamin. If they use poor forms of nutrients, then it is not likely to cause any imbalance - just in your wallet. If you start low and work up, you greatly reduce the risk of agitation. Best Dr Ben
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• CLARIFICATIONS at 1/7/12 6:09 PM
  • I am enjoying this tablet. It makes me feel grounded and secure. I have most of my relatives taking it now. I have two more questions that will help specific relatives:
    
    1) Is the Metafolin portion of this supplement absorbed sublingually, like the B-12 component is? Or does the Metafolin portion mainly get absorbed by the stomach when it is swollowed?
    
    2) You say that getting too much methylfolate can be "too much of a good thing", or as bad as not getting enough. This worries people. So we want to know, how dangerous is this? Is the resultant agitation and irritability just a feeling of discomfort? Or is the body suffering from an imbalance as much as it would be harmed by a deficiency? I have not been able to find where you clarify this disturbing concern anywhere on your site.
    
    Thanks! Dave
  • Hi Dave - Great questions. Let me quickly say that the population that I work with is very ill and highly sensitive so I am extra careful in my recommendations. The general population is not likely to experience any ill effects from taking methylfolate in higher amounts. According to the Alt Med Review: Side Effects and Toxicity of Methylfolate: In doses typically administered for therapeutic purposes, 5-MTHF is considered non-toxic. At doses of up to 50 mg daily, gastrointestinal complaints, insomnia, irritability, and fatigue have been mentioned as occasional side effects. Folic acid and 5-MTHF are considered safe during pregnancy, with a recommended intake of 800 mcg daily. To answer your questions: 1) The metafolin is going to be directly absorbed just like the methylfolate - sublingually. 2) Taking too much of anything is not good. Is taking too much methylfolate dangerous? In most people, no. It is not going to cause long term issues or death or a serious health concern - and not even any side effects. People take upwards of 50 mg of methylfolate daily for their depression or other mental dysfunctions. I am very conservative when it comes to dose suggestions as I don't like people being 'macho' and thinking that if they take 10 mg of methylfolate, that will be better than 1 mg. Sometimes yes it will and sometimes it won't. What could you experience if you do take too much methylfolate? - Irritability - Anxiety - Nausea - Headaches - Insomnia Will these symptoms go away upon reducing the levels of methylfolate or stopping it? - Yes Will these symptoms go away quickly? - In most people - yes - these symptoms will stop within 24 hours if not earlier. Can you 'neutralize' these side effects faster if they occur? - Many times, yes. How? - By taking niacin as niacin increases the absorption of methyl groups and also increases the breakdown of glutamte - which is the excitatory neurtransmitter. - By taking vitamin B6 - for many people - as B6 converts glutamate to GABA and GABA is the inhibitory neurotransmitter. As a physician, it is my job to: - Inform - Educate - Do no harm That said - I encourage people to start low and work up carefully to avoid these side effects. If I have 'scared' you - in a way, that is good - because you - and others - will take my recommendations to go slowly seriously. :) Methylfolate in high doses appears to be much safer than taking folic acid in high doses. As of now, research does not show any long term ill effects of excessive methylfolate - except in those who are bipolar. Why bipolar? Those with bipolar already have issues breaking down glutamate which is why they do so well on high doses of vitamin B3 (niacin) and I bet they'd also do very well on vitamin B6 and magnesium. I hope this has been informative and has reduced the anxiety of your relatives. My apologies for making your desire to help your family more difficult. I admire your kindness and desire to help them. Best, Dr Ben
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• yeast at 1/18/12 10:15 AM
  • I was just wondering if your supplements contain yeast. The 5-MTHF/methylcobalamin tablets list other allergens that aren't in the product, but not yeast.
    
    Thanks,
    Marikate
    
  • Hi Marikate, The Sublingual active B12 with Metafolin and L-5-MTHF by Seeking Health do not contain yeast. Kind regards, Team HealthE Goods
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• Sublingual B12 with Metafolin at 2/4/12 12:33 PM
  • Hello,
    
    Our family is taking Homocystex. Two in the family have two
    copies of the C677T mutation. I have one copy of A and one of C. Would you advise I take Sublingual B12 with Metafolin with the
    Homocystex?
    
    I read on another e-mail about the recommendation of NAC
    for detoxing. Is this something one has to be on indefinitely
    even if lab work shows a person after a course of NAC
    is free of heavy metals?
    
    Is there anything else that you sell that could help someone
    that has obsessive tendencies ? This person has been on 2 Metanx
    for one year. The obsessive tendencies contain to plague this
    family member. They have switched from Metanx to 4 Homocystex for 4 weeks. They are also taking 4 Thorne Nia-safe a day. The
    Nia-safe seems to take the edge off, but the obsessiveness
    does not go away.
    I would appreciate any information.
    Thank you!
  • Hello - They may be overmethylating themselves which is why the niacin is helping them. They also may have a COMT or MAO A or CBS mutation which is increasing the issue of the MTHFR mutation. I greatly suspect that they are taking too much methylfolate and that a lower amount of methylfolate should be used along with an increased amount of niacin in the form of nicotinic acid. There are other things also of course which need to be evaluated by their doctor. I am happy to work with you and provide more specifics via a consult. I cannot provide more information than this unfortunately without more information from your end. You may schedule a consult by calling 800-689-8221 Best Dr Ben
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• 'acute' applications at 4/8/12 7:41 AM
  • I'm chemically hypersensitive and recently had exposure to lawn chemicals that effected me badly. In such a case, is there something I can take to help my body deal with such exposures when they accidentally occur? (I'll be starting the recommended folate 800mcg & methyl B12 1000 mcg next week).
    
    Thank You *^^*
    
    
    
  • Hello - In situations like this, it is best to contact the manufacturer of the lawn chemicals and learn what the MSDS (Manufacturer Safety Data Sheet) states to do. A sauna may be very effective here along with liver support, coconut oil, and fish oil. Consider taking: - Liver Nutrients: 1 capsule with breakfast and 1 with dinner. - Optimal Fish Oil: 2 capsules twice daily with a meal Do tell your doctor about your experience. If you'd like to find a doctor trained in chemical sensitivity, I recommend you visit www.naturopathic.org or www.aaemonline.org In health, Dr Ben
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• Medication in pregnancy at 7/28/12 10:38 AM
  • I was going to try and supplement with the vitamins for the amount in metanx, so I would not need a prescription, during my next pregnancy. I am currently on folgard and have read it is not really good to be taking for compound hetero MTHFR, is it ok to take this supplement twice a day and additional l-methlfolate to bring up to the dosing of one tablet of metanx? I would also include a supplement for the B6. Thanks

  • Hello - 

    If it is ok with your doctor, one may take the equivalent amounts of methylfolate, methylcobalamin and vitamin B6 as found in Metanx.

    Consider:- Active B12 with Metafolin- L-5-MTHF- Magnesium Plus: contains 20 mg of pyridoxal-5-phosphate per capsule along with 100 mg of magnesium.

    One may also consider HomocysteX as it contains all three nutrients

    In health,

    Dr Ben

     

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• Why Magnesium Stearate? at 9/4/12 9:01 AM
  • I just read an article on your website about Magnesium Stearate...I thought if I purchased your product, it wouldn't contain this ingredient...but it's in your B-12. I haven't checked your other products, but I'm doing that now. I don't want any products that contain MS.

  • Hello - 

    Seeking Health does not use magnesium stearate in products that are in capsules.

    Magnesium stearate is only found in products by Seeking Health which are:- chewable- sublingual- extended release

    We are working on developing all products without magnesium stearate but in chewable, sublingual and extended release, it is very difficult to do so.

    Since the absorption is excellent in sublingual, chewable and extended release, we are much less concerned about magnesium stearate in these products.

    You will NEVER find magnesium stearate in any vegetarian capsule or gelatin capsule by Seeking Health.

    In health,

    Dr Ben 

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