Seeking Health HomocysteX Plus

Questions on Seeking Health HomocysteX Plus

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• B-12 absorption problem at 9/12/11 10:40 AM
  • I have an absorption problem, especially with B-12, I normally have to take injections. Will I be able to absorb this form?
  • Hello - This is the most active form one can have for oral vitamin B12 - methylcobalamin. Vitamin B12 requires stomach acid in order to be absorbed. If anyone is taking antacids, vitamin B12, folic acid, calcium and iron are commonly deficient. It is imperative that the acid reflux and gastritis be healed so one can be taken off of antacids. There are also autoimmune conditions which are known to destroy the body's ability to make intrinsic factor. If you have any of these problems, continuing with an injectable form of vitamin B12 is a good idea. You may also open the capsule of Homocystex, mix it in a small amount of water and hold it in your mouth. This will increase the absorption of the vitamin B12 as it will be absorbed sublingually. You can tell if you are absorbing the vitamin B12 in HomocysteX if your homocysteine levels are staying within normal limits and your methylmalonic acid levels are low or in the normal range. In health, Dr Ben
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• safe for toddler? at 9/12/11 3:41 PM
  • Would this be safe to give my 17 month old daughter ground up in her food?I am homo a1298 copies. So I know she has at least one copy. If this is not safe for her, what can I give her to make sure she is getting enough b vitamins?
  • HomocysteX is quite safe. If you are breastfeeding, it is more ideal for you to take HomocysteX orally and then have your child get it via your breast milk If you are not breast feeding, then I recommend you talk with your doctor about using HomocysteX for your 17 month old daughter. I personally use HomocysteX on my children and have been for some time. One cannot get the most active form of folate from food - it has to be supplemented. The A1298C MTHFR mutation also requires further nutrients beyond what HomocysteX offers. There is a major detoxification and methylation problem for those with A1298C mutations. It is impossible to know which nutrients one with A1298C mutations should take without further methylation lab testing. For your daughter, consider using 1/2 capsule of HomocysteX mixed in some organic applesauce. Give once daily. I do recommend testing your child now for the MTHFR mutation and also Methylation to see what is going on with her. The amount of HomocysteX you and your daughter should take is based upon what lab values are found. Make sure you and your daughter both take a quality fish oil such as Optimal Fish Oil Liquid. It tastes quite good so should be easy for you to mix it in some food or give it to her directly. The Optimal Fish Oil capsules are more potent so they would be better for you to take -or the Optimal Krill Oil would be even better for you. You may poke a hole in the Optimal Krill Oil gel cap and squeeze the contents onto some food for your daughter. This would be very beneficial. In health, Dr Ben
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• dosage at 9/24/11 7:57 AM
  • Before placing my order I would like to know what the dosage is for my daughter who is hoping to conceive again after # 3 miscarriages. She is homo A1298 and my husband who is compound hetero c677t and A1298C. I haven't been tested yet but I assume I'm at least positive for the A1298C. I'll be placing multiple orders.I read somewhere that for each copy you should take 1000 mcg of folate.Is this true?
  • Hello - Those with homozygous A1298C tend to be loaded with heavy metals and other chemicals because they have a decreased ability to get them out of their body. This may be a significant factor which is not normally addressed by physicians. I recommend you consider a prenatal with active folate in it such as Prenatal Pro: http://www.healthegoods.com/prenatal-pro-180-vegetarian-capsules.html I recommend your daughter look at her methylation profile via a lab test by Doctor's Data: http://www.healthegoods.com/methylation-profile-doctors-data.html It would be a benefit also to identify exactly what her nutritional needs are and potential toxicities via the ION Panel by Metametrix. This is an expensive test but it is highly effective. I want you to know that I do NOT profit from this lab test. http://www.healthegoods.com/ion-profile-blood-urine-metametrix.html I am available to do a consult with her once we get the results back for this ION Panel. I do recommend she consider it. Insurance companies do not cover it. http://www.healthegoods.com/consult.html I also recommend she look at her progesterone levels to make sure they are healthy. Talk with her doctor about this. You need to have your daughter test her partner for MTHFR mutations also. You need to know what the potential risk is of her baby obtaining another MTHFR mutation from the father. I do not recommend taking just folate for those with MTHFR. I recommend taking only the active forms of folate which are 5-MTHF or L-5-MTHF. HomocysteX contains L-5-MTHF You should be taking a multivitamin that contains the active 5-MTHF along with the methylcobalamin and active B6. If you don't, your MTHFR mutation is not allowing full absorption and utilization of these nutrients thereby causing dysfunction. I recommend you and your husband consider Optimal Multivitamin by Seeking Health: http://www.healthegoods.com/optimal-multivitamin-240-vegetarian-capsules-seeking-health.html Consider 3 capsules in the AM with breakfast, 3 at lunch and 2 more with a snack around 3 PM for ideal energy and health. If that is too hard for you - no worries - just try and get 3 capsules in at breakfast and 3 at lunch. Do not take after 3 PM as it may interfere with sleep. HomocysteX is a potent formulation which has an unique formulation for lowering homocysteine and providing nutrients for methylation. I am not sure what the general recommendation of 1,000 of MTHF is for each mutation. I do not think there is a set recommendation as each individual is unique, consumes different foods, exposed to different things in the environment and have different levels of MTHFR function. This is why I recommend the Methylation Profile by Doctor's Data. This way you can see if one is methylating well and eliminating homocysteine and s-adenosylhomocysteine. Once you know the results of the Methylation Profile, you adjust your nutrient intake accordingly. Should you need more L-5-MTHF than is found in the HomocysteX, you may take L-5-MTHF directly: http://www.healthegoods.com/l-5-mthf.html This is an effective way to adjust your MTHF levels and is also less expensive - and safer. Optimal Krill Oil is highly recommended to help combat damage caused to the cell membranes from chemical exposures and heavy metal exposures. Optimal Krill Oil contains a fantastic antioxidant which is needed in such a pro-oxidative mutation: http://www.healthegoods.com/optimal-krill-oil.html NAC is a nutrient that should be considered for all who are not pregnant. This helps to mobilize and eliminate chemicals and heavy metals out of the body: http://www.healthegoods.com/nac-n-acetyl-l-cysteine-90-vegetarian-capsules-seeking-health.html Probiotics are also a crucial component to help bind some toxins that come in through the food or drink. Research shows that some strains of bacteria actually help bind BPA and eliminate them from the body. I recommend your daughter, you and your husband take 1-2 capsules of ProBiota 12 nightly after dinner. You may likely notice improved digestion, less gas and bloating, improved immune function, improved skin health and less fatigue. http://www.healthegoods.com/probiota-12-maximum-support-50-billion-cfus-twelve-species-probiotic-60-vegetarian-capsules-seeking-health.html Should you have further questions, please do ask. I do recommend a free 15 minute consult as well should you desire that. In health, Dr Ben
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• Already converted? at 9/27/11 9:12 AM
  • Hi - I just want to be really clear: this product is the already converted b vitamin stuff that MTHFR patients need, correct? My body doesn't have to methylate anything here?
    
    My doctor prescribed Deplin (which I know is missing the TMG), but is open to me using whatever I can find. She wasn't sure that this product is already converted (but, I don't think she checked it out).
    
    Thanks for any clarification!
    
    
  • Hello - HomocysteX contains the L-5-MTHF form of folic acid. The L-5-MTHF is the methylated form which those having MTHFR mutation need. Your body does not need to methylate any ingredients found in HomocysteX as they are already methylated. The vitamin B12 is in the form of methylcobalamin. The folic acid is in the form of L-5-methyltetrahydrofolate. The vitamin B6 is also already phosphorylated as is the vitamin B2 making them highly absorbable as well. The added TMG, which is betaine, bypasses the MTHFR mutation completely making it very effective in homocysteine metabolism. I have kept the level of L-5-MTHF at 800 mcg as the other ingredients found in HomocysteX greatly support homocysteine metabolism. Should your doctor want you to take additional methylated folic acid, consider L-5-MTHF 1000 by Seeking Health. Each capsule provides 1,000 mcg of methylated folic acid in the form of L-5-MTHF. http://www.healthegoods.com/l-5-mthf.html This makes HomocysteX an affordable solution and helpful to many because not everyone needs such high doses of methylated folic acid. L-5-MTHF is an expensive and potent ingredient. Should one need additional methylated folic acid, it is easy to obtain with L-5-MTHF by Seeking Health. In health, Dr Ben
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• Miscarriages, Rheumatoid Arthritis at 10/6/11 8:09 AM
  • I have a friend who has suffered several miscarriages. She has also been diagnosed with Rheumatoid Arthritis. Could RA come from the MTHFR gene mutation? Should she be tested for this?
    Would Homocystex benefit people who do not have the gene mutation?
    Thanks,
    Diana
  • Hi Diana - I'm sorry to hear about your friend experiencing miscarriages. Rheumatoid arthritis has numerous causes but the good news is I can help her completely overcome it if she is willing to make lifestyle and dietary changes, she may want to schedule a consult with me: http://www.healthegoods.com/consult.html The MTHFR mutation is highly prevalent in the population - especially some specific populations like Italians and Mexicans. HomocysteX may benefit people who do not have MTHFR if they experience elevated homocysteine, B12 deficiency, depression, chemically sensitive, have chronic disease, low methylation and others. If your friend has had several miscarriages, she should definitely be tested for MTHFR mutations: http://www.healthegoods.com/mthfr-test.html She should also be tested for poor methylation as methylation is the critical biochemical process for the human body: http://www.healthegoods.com/methylation-profile-doctors-data.html Best, Dr Ben
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• MTHFR other clotting genes, serious family history of stroke and heart attack at 10/13/11 6:12 AM
  • Dear Dr Ben
    
    I have recently been diagnosed with
    
    MTHFR (C677T) mt/mt (homozygous)
    PAI-1 4G/4G
    EPCR (4600 A>G /EPCR 4678 G>C) (A/A, C/G)A1/A2
    
    I am trying to conceive one blocked tube, and the tests above were done by a fertility clinic because I have a family history of strokes /heart disease. My mother has alzheimers/dementia caused by blockage of a carotid artery in the neck and lack of oxygen to the brain. She has had 3 strokes and now has an extremely low standard of living. My Dad had 3 heart attacks, triple heart bypass and is dead. I have both genes from my parents homozygous and 4G/4G.
    
    I have been told to take baby aspirin 75mg daily. Also 5mg of folic acid and clexane during pregnancy. From what I have read you would recommend HomocysteX is that correct? Is there anything else I should take? Is 800mcg of
    Folate (as Metafolin L-5-methyltetrahydrofolate) enough or should I take L-5-MTHF 1000 as well?
    
    Any thoughts would be greatly appreciated, I am in the U.K and my general practitioner is not very helpful. I will be doing ivf in the future and would also want to take the right thing for the rest of my life. I don't think I have a dormant gene considering what I have just seen my parents go through.
    thanks so much
    
  • Hi there - Thank you for your question. Given your history and complexity, I highly recommend a consult. http://www.healthegoods.com/consult.html HomocysteX may be beneficial along with additional L-5-MTHF. It is best to monitor labs and symptoms in order to obtain an ideal amount of nutrients. Too much or too little can pose problems. Those with homozygous C677T mutations have been taking 2-3 capsules of HomocyteX twice daily. The active folate in HomocysteX is much more bioavailable than 5 mg of standard folic acid - especially with a homozygous MTHFR mutation. Baby aspirin is a good idea to take. Flow Fx may be indicated as well as it helps break down Fibrin which is the building block of blood clots. Flow Fx contains 50 mg of Nattokinase in a quality form without fillers and flow agents. On my www.MTHFR.net website, a woman recently commented about nattokinase: "I wanted to comment because I have had several miscarriages and want to share what I did with my last pregnancy and kept her alive. I was on heparin for 3 preg. and lovenox for the next all ending in miscarriages. I added Nattokinase and she lived! Follow what Dr. Ben says paying special attention to include nattokinase. I was not on any heparin or lovenox, only nattokinase, and baby aspirin. Blessings and well wishes, Tami" Nutrients recommended for those with homozygous MTHFR mutations: Optimal Krill Oil, NAC, Active CoQH, Flow Fx, Optimal Vitamin C, HomocysteX, Optimal Multivitamin, ProBiota 12 Powder. These may be found here: http://www.healthegoods.com/brands/seeking-health.html I also recommend the addition of Xylitol Gum as it helps prevent cavities in newborn children which is amazing. http://www.healthegoods.com/xylitol-fruit-gum-biogenesis-ear-infection.html I am available for consults should you need more individual information. I am happy to help - even those overseas may schedule consults. In health, Dr Ben
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• Homocystex at 10/22/11 10:21 PM
  • I have heard that patients with MTHFR should take these supplements 3x a day. Is there any reason that could be too much, in your opinion?
    
  • Hello - It depends. Depends on: - Age - # MTHFR mutations - Diet - Lifestyle - Other supplements taken I believe the least amount is ideal but you have to know what the least amount is. The Methylation Profile helps determine that. I always recommend starting out with 1 capsule of HomocysteX for a few days, see how you feel and then increase from there. I do not recommend taking HomocysteX within 5 hours of going to bed as it may keep you awake. 3 capsules is a pretty standard dosage of HomocysteX. In this case, I'd recommend 2 in the AM and 1 capsule at lunch or around 2 PM or so. Or - you may take one on getting up, one at lunch and another around 5 PM. This way your blood levels of these critical nutrients stay where they should be and you absorb more of the nutrients as well. In health, Dr Ben
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• MTHFR program at 10/29/11 4:07 PM
  • Hello,
    
    I love all the information on this issue on your site. From what I can see you seem to recommend the Homocystex, Krill oil and NAC along with a good vitamin and probiotic to assist with the MTHFR issue. I have both types of this defect. I have heard that Same is a great product to take also for methylation. Do you think that it would also be helpful or is it really necessary to add to the basic items already mentioned? I want to do the best I can for the issue, but don't want to do anything that is not needed.
    
    Thanks, Sharri
  • Sharri - You are right in that I commonly recommend the following for adults with MTHFR mutations: HomocysteX, Optimal Krill Oil and NAC along with Optimal Multivitamin and ProBiota 12. Some people do great with this while others need to have it altered. HomocysteX contains nutrients which naturally lead to making SAMe. It is not good to take too much of any nutrient - especially methylators like SAMe - as it can cause ill effects. I always recommend starting simply and then expanding on that as long as you feel good or you are noticing improvement. If you take too many things at once and you feel not so hot, you do not know what is causing it. Also, if you are taking a lot of things at once, you may feel great initially for a few weeks, but then may get not so hot feelings down the road. This requires alteration in dosages and what you are taking. If you or anyone that you know of are homozygous C677T or compound heterozygous A1298C and C677T, then taking Flow Fx may be beneficial. These mutations are more prone to clotting and Flow Fx help reduce fibrin. Fibrin is a main building block for blood clots. You can tell if you need further methylation support by ordering the Methylation Profile. http://www.healthegoods.com/methylation-profile-doctors-data.html If you want to know deficiencies and excesses along with levels of fatty acids and metabolites, the ION Panel by Metametrix is highly recommended: http://www.healthegoods.com/ion-profile-blood-urine-metametrix.html The ION Panel is expensive but it truly helps pinpoint issues quickly and effectively. It basically removes the guessing by a fair amount. So in short, no - I do not recommend the SAMe or Methionine above what you are taking currently - not unless you are still experiencing symptoms. If you are not improving the way you'd like, I highly recommend consulting with me so we can alter what you are doing and get you on the right track. http://www.healthegoods.com/consult.html Again - the ION Panel comes highly recommended as well. To let you know, I do NOT profit on the ION Panel. It simply is an expensive test. In health, Dr Ben
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• MTHFR c677t and recently diagnosed with Graves disease, I am 5 months postpartum at 11/14/11 2:15 PM
  • I am taking Deplin, B-12 injections and a baby aspirin for my genetic defect. I am taking iodine, lithium and Betain HCL for the Graves. In addition I am taking D3, calc & mag caplet, mineral supplement and glutathione. I am miserable, my joint point is awful. I can actually feel my adrenal spots in my hands and feet hurt. I know an adrenal issue is at hand. I also had the MMR vaccination the day after giving birth..not in my right mind(not lucid)!! I cannot produce enough milk to feed my baby, at times I can feel my thyroid pulsing. Please, please help. I have Dr.'s that walk the line and are not thankfully throwing a bunch of pharmaceuticals at me. But nothing is really working here....
    
  • Hello - Sorry you are not feeling well. If you have Grave's and are taking iodine, that may be a problem. Talk with your doctor about this. I highly recommend avoiding wheat completely as it is linked to autoimmune thyroid disorders like Grave's. Glutathione could be making your joints hurt as you may be detoxing too quickly. You may be taking too much methylfolate. Deplin has a lot. The MMR vaccine likely has mercury in it which is known to shut down a major biochemical pathway - MTR. This pathway is needed to detoxify and make methyl groups needed for neurotransmitters. Consider taking 1 capsule of HomocysteX the first day and then 1 capsule twice a day. You will have to experiment which dose works well for you as everyone is different. If you feel agitated, you are taking too much. You may find taking one capsule every other day be excellent for you or you may find you need to take 1 capsule three times a day every day. Vitamin D3 is critical. Measure your vitamin D3 levels and consider taking 3 drops a day of Vitamin D360. http://www.healthegoods.com/liquid-vitamin-d360-1-oz.html Consider Probiota 12 capsules and take 2 after dinner for 2 weeks and then reduce to 1 capsule and stay on that. http://www.healthegoods.com/probiota-12-maximum-support-50-billion-cfus-twelve-species-probiotic-60-vegetarian-capsules-seeking-health.html Your infant should be on 1/4 teaspoon a day of Probiota Infant: http://www.healthegoods.com/pro-biota-infant-powder-60-grams-seeking-health.html Consider 1 capsule a day of Active CoQH: http://www.healthegoods.com/active-coqh-60-softgels.html Make sure you are eating some form of protein every couple hours. A whey protein is great unless you are intolerant to whey. This will help make more milk. Get on Fenugreek to help make more milk. Stress limits milk production and I understand this is an issue. There are other mutations which may compounding factors here. There is a lot going on and one must take it one step at a time. For starters, get off wheat completely starting today, consider stopping the iodine and consider the suggestions above. This is just information for you to consider - not treatment, advice or prescriptions. Best Dr Ben
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• Product odor? at 11/15/11 3:09 PM
  • I recently ordered HomocysteX and when I opened the bottle I noticed the product has a very strong odor, sort of like sour milk. I just wanted to check if this was normal or could there be something wrong with it?
    
    Thank you.
  • Hello - The HomocysteX has a strong odor due to the TMG. This is a sour smelling and tasting nutrient. The color of slight orange is due to the methylcobalamin. Thank you for checking! Best Dr Ben
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• Confused at 11/28/11 11:24 AM
  • I am taking Methionine and read that it increases Homocystine levels which is not good for the heart. Can I take Homocystex to keep the homocystine levels in check or is it better to take L5-MTHF?
    
    Also, what is the difference between the two? From the description they seem to do the same thing. HomocysteX contains L5-MTHF so whats the point of taking it solely or seperately?
    
    LaLa
  • Methionine can increase homocysteine levels - that is correct. You can take HomocysteX to keep support healthy homocysteine levels. It is better to take a comprehensive approach to lowering homocysteine rather than just supporting one pathway. HomocysteX contains nutrients which support the lowering and maintenance of homocysteine through at least 4 biochemical pathways. Taking just L-5-MTHF supports the lowering of homocysteine through 1 pathway. HomocysteX can also increase methionine levels indrectly through TMG. TMG found in HomocysteX processes homocysteine into Methionine. You may find that you need to reduce your dose of Methionine while taking HomocysteX. Some people do not do well when taking methylcobalamin or TMG which is why Seeking Health also offers stand along L-5-MTHF. Some people's methylation is over active We have L Methionine available here if needed: http://www.healthegoods.com/methionine-100-capsules-seeking-health.html And L-5-MTHF is here: http://www.healthegoods.com/l-5-mthf.html
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• Homocystex while taking Levothyroxin at 12/14/11 8:19 PM
  • Good evening Dr. Ben,
    
    I have just been prescribed Levothyroxin due to my TSH levels now in the 60 range (yes 5* what it should be), I believe this to be post partum thyroidism. I was first diagnosed with Graves. I Plan on taking first thing in the AM. I currently take Seeking Health Homocystex (love it, I have replaced this Deplin), Active CoQH & Liquid Vitamin D360 and the Probitioic. I of course also take a standard multi-vitamin. Is there any harm in taking the Seeking Health products with this prescription. I never take prescrition drugs, however with the MTHFR 677, I am feeling desperate and would like to avoid a stroke due to this high of a TSH level. I want to stabilze and then transfer to armour. Any advice would be greatly appreciated. My Mother has a phone consult with you tomorrow, she suffered a massive stroke in 2009 due to the double 677 marker.
    
    Thank you, Angela.
  • Hi Angela - It is ok to take thyroid meds while taking these supplements. There is no interaction. I highly recommend reading the book: Paleo Solution by Robb Wolff. This book explains and supports my telling you to avoid wheat from your diet. (And I know i need backup for this ;) Please avoid all wheat and dairy for a few weeks and see how you feel. If you are living in the same area as your mother, then you may be exposed to high amounts of pesticides, herbicides and insecticides. These greatly interfere with thyroid function. Did your docs test your anti-TPO and anti-TG recently? Taking selenium, magnesium, iron (if low) and zinc are critical for thyroid function. You low in iron? Celiac is also related to thyroid issues (gluten...) I recommend getting off a standard multivitamin and switching to Optimal Multivitamin as it has methylfolate and superior forms of nutrients. Standard multis are just that - standard. You deserve better. Consider three capsules with breakfast and three at lunch: http://www.healthegoods.com/optimal-multivitamin-240-vegetarian-capsules-seeking-health.html I also recommend you consider Thyroid Support by Gaia. Excellent formula - it is what my wife uses. http://www.healthegoods.com/thyroid-support-60-capsules-emerson-ecologics.html Consider taking 1 to 2 in the AM. Tell your doctor you'd like to add this in so you don't have to take so much levothyroxin. Do not add this in unless your doc ok's it. Keep me posted. Best Dr Ben
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• Homocystex while taking Levothyroxin at 12/21/11 5:54 PM
  • Good evening Dr. Ben,
    
    Thank you for your response, I was concerned about any negative interaction.
    
    I opted for a second opinion and have decided to take armour thryo at 60MG to an increase to 120 MG's in a week instead of the 75MCG's of levothyroxin.
    
    My TPO actually came in today, this was over 1000 (32* ref range). My TG is within range.
    
    Since we first spoke in November, I placed myself (my Mom has joined me) on a gluten/wheat free diet. I am not feeling any better, unfortunately. In due time I sure it will be a benefit. I currently try to stay away from Dairy, I use butter very rarely.
    
    I was not low in iron. My Vitamin D was within range but on the low end at 38ng. I am now taking three drops of seeking health D3. I also am taking cod liver oil (1 teaspoon) for the terrible joint pain I have been dealing with since my sixth week post partum. I just began taking the cod liver oil, I am sick of the pain and need some kind of relief.
    
    I do live in the same area as my Mom, I never thought about the pesticides playing a part in this mess. My formal genetic testing also came in today. I am a dual 677, not the one as I had first thought.
    
    I had a terrible pregnancy, projectile vomiting for nine months. PP I had a six week adrenaline rush and have crashed and burned ever since. I am certain this all comes down to toxicity levels (heavy metal), the MMR vaccination I should have never been offered after being in labor for more then 24 hours. Once I get into the new year I will schedule a consultation in hopes to have a better outlook for 2012:)
    
    Thank you for your wonderful work and have a wonderful evening.
    
  • Hello - With TPO over 1000, a gluten free diet is key, along with the D3 - both of which you are doing which is great. Your D3 is low - should be at least 50. Taking 3 drops a day is good - not too low or too much. I also recommend you consider selenium at 200 mcg a day. Zinc is also needed. Taking a trace mineral complex is easiest. Make sure to take trace minerals with food. I recommend with dinner. Here is Trace Mineral Complex - consider 1 a day with dinner. http://www.healthegoods.com/trace-mineral-complex.html SInce the immune system plays a major role in how your TPO is doing, it needs to be regulated. Probiotics increase T regulatory cells which help control inflammation and autoimmune responses. Consider taking 2 capsules of ProBiota 12 after dinner on a nightly basis: http://www.healthegoods.com/probiota-12-maximum-support-50-billion-cfus-twelve-species-probiotic-60-vegetarian-capsules-seeking-health.html For your little one, I HIGHLY encourage you to provide him/her with a 1/4 teaspoon of ProBiota Infant every day until they are 2 yrs old. Critical for healthy immune system development, healthy skin, and reducing the absorption of toxins. http://www.healthegoods.com/pro-biota-infant-powder-60-grams-seeking-health.html For joint pain, consider ArthroGenX. It has a comprehensive blend of nutrients to support joint health and also to help reduce joint pain. Consider 2 capsules in the AM at least 20 minutes before breakfast and 2 capsules in the afternoon before lunch and 2 more capsules before bed. Do this for a few weeks and then reduce to 2 capsules before breakfast and 2 capsules before bed. http://www.healthegoods.com/arthrogenx-120-capsules-by-biogenesis-nutraceuticals.html If you are up to a moor mud bath, this is very effective at relieving pain: http://www.healthegoods.com/torf-czech-natural-moor-mud-for-bath-and-body-wrap-250-ml-torf.html Add 500 ml to a bath along with a couple pounds of epsom salt. You may buy inexpensive epsom salt from www.Saltworks.com Applying castor oil to your joints may help. HomocysteX may help reduce the pain as well if related to elevated homocysteine or low methylfolate. Test your infant for MTHFR once they get a bit bigger. If you are breast feeding, he/she will get some of the nutrients through your breast milk. Best Dr Ben
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• HomocysteX at 12/31/11 1:31 PM
  • Recently my doctor switched my daughter to Deplin from
    Thorne MTHF -5. She has found that her 200 patients that have
    a C mutation do best with pharmacy brands. I would love
    your thoughts on this. How would you compare HomocysteX
    to the pharmacy brands?
  • Hello - The methylfolate that is in HomocysteX is actually pharmaceutical grade - and made by Merck - a pharmaceutical company and manufacturer of Metafolin - which is the most respected form of methylfolate. The pyridoxal-5-phosphate is also pharmaceutical grade. The only difference between HomocysteX and pharmacy brands is that HomocysteX does not have any additives, colors or flow agents which all the pharmacy brands have that I have seen - including Deplin. You can see all the pharmacy-grade recommendations for MTHFR here: http://mthfr.net/comparison-of-homocysteine-support-products/2011/09/13/ I also prefer that people take methylfolate along with methylcobalamin, pyridoxal-5-phosphate, riboflavin-5-phosphate and TMG. This is much more effective in lowering homocysteine and also increased methylation support. We also offer multivitamins with methylfolate, sublingual B12 with methylfolate and methylfolate by itself. Sublingual Active B12 with Methylfolate: http://www.healthegoods.com/sublingual-active-b12-metafolin-seeking-health.html All multivitamins by Seeking Health contain methylfolate. Here is our single ingredient methylfolate which is free of all additives and flow agents and contains 1 gram of methylfolate in the form of Metafolin - made by Merck. http://www.healthegoods.com/l-5-mthf.html Best Dr Ben
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• Question about HomocysteX at 1/8/12 4:17 PM
  • Hello Dr. Ben,
    
    My husband recently tested positive for Homozygous C677T. His
    homocysteine level is 8.5. I tested positive for C677T and A1298C.
    I am a thyroid cancer survivor.
    
    Would you recommend HomocysteX for both of us? I tried 15 mg.
    of Deplin and I felt jittery. Now I take 7.5 mg. My daughter tried 2 Metanex a day for one year. She tolerated it well. Her system is
    still not balanced, but she did not have adverse effects with it.
    We both have low blood sugar. Before she
    started the Metanex her homocysteine level was 3.
    
    How much HomocysteX would equal 2 Metanex?
    
    I would appreciate any information. Thank you so
    much for what you are doing!!! I pour over your site
    for hours to learn as much as I can. Hopefully our
    family will be able to someday encourage others too.
    
    Sincerely, LSue
  • Hello - Deplin 15 mg is a lot and without methylcobalamin, I find it not a good idea for many people. Each Metanx tablet = 3 mg of methylfolate, 2 mg of methylcobalamin and 35 mg of pyridoxal-5-phosphate. If not taking into account the other nutrients found in HomocysteX (TMG and Vitamin B2 - both of which are critical), one needs to take 4 capsules of HomocysteX compared to 1 MetanX. HomocysteX is also free of all colorings, preservatives and additives while Metanx has these things. From the sounds of it, you all should do well with HomocysteX. The one negative review we have on HomocysteX: - I really think this woman has an additional CBS mutation which is making her feel worse. If people have a CBS mutation + MTHFR, they must first address the CBS mutation and then proceed to taking methylfolate and methylcobalamin and other sulfur nutrients - and B6. Make sure you all are getting plenty of Vitamin D3 (4,000 IU a day at least) which is 2 DROPS of Vitamin D360: http://www.healthegoods.com/vitamin-d360-by-seeking-health.html Optimal Multivitamin: http://www.healthegoods.com/optimal-multivitamin-240-vegetarian-capsules-seeking-health.html ProBiota 12: http://www.healthegoods.com/probiota-12-maximum-support-50-billion-cfus-twelve-species-probiotic-60-vegetarian-capsules-seeking-health.html Liver Nutrients: http://www.healthegoods.com/liver-nutrients-60-vegetarian-capsules-seeking-health.html Optimal Brain: http://www.healthegoods.com/optimal-brain-30-vegetarian-capsules-seeking-health.html These are the core nutrients I often recommend for everyone - regardless of feeling excellent or not. With all your MTHFR in your family, these nutrients are definitely needed. Keep me posted how you do. Best Dr Ben
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• Homocystex and Metafolin at 1/14/12 4:57 AM
  • Hi, Dr Ben
    
    I would like to know if the l-methylfolate in Homocystex is Merk's licensed/optimized.
    
    Is it useful to treat depression?
    
    Thanks!
    
    Paloma
  • Paloma - The L-methylfolate is Merck's Metafolin, yes. It can be useful to support those with symptoms of depression if the symptoms relate to low levels of methylfolate. You may also be interested in the other delivery methods of Metafolin: - Sublingual Active B12 with Methyfolate (which is Metafolin) provides 1 mg of methylcobalamin and 800 mcg of Metafolin http://www.healthegoods.com/sublingual-active-b12-metafolin-seeking-health.html - L-5-MTHF which provides 1 mg of Metafolin per capsule http://www.healthegoods.com/l-5-mthf.html Always start low and work up in amounts. It is best to take any of these on an empty stomach. Best Dr Ben
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• Inquiring about absoption of methylcobalamin in Homocystex Plus at 3/6/12 6:35 AM
  • Hi there,
    I was diagnosed with heterozygous MTHFR. I currently am taking 4 different supplements of methylated B's seperately, which is why I am excited that I found your product, and I plan to buy it once I run out. Now, my only concern is that I have been taking sublingual doses of B-12 and I have been told that just swallowing it, the body doesn't absorb as much. What is your take on this? Should I be supplementing additional to this supplement, should I mixed Homocystex Plus with water and hold in my mouth, or because I am heterozygous, my body does a better job of absorbing it and I shouldn't worry?
    
    Thank you so much for you help,
    Nicole Warren
  • Nicole - There are studies out there that show similar absorption results between sublingual, injection and oral intake of vitamin B12. The issue with b12 absorption is in people who have pernicious anemia which is caused by an autoimmune attack on part of their vitamin B12 absorption function. Since you are heterozygous MTHFR - I assume C677T - then taking a couple capsules a day of HomocysteX Plus should suffice. You may open the capsule, mix in some juice, place in mouth, hold and then swallow if you like. I think that is unnecessary though. I also want you to know about Optimal Multivitamin which also contains methylfolate and methylcobalamin: http://www.healthegoods.com/optimal-multivitamin-240-vegetarian-capsules-seeking-health.html I also want you to read and understand the side effects from methylfolate so you understand if you are taking too much or not: http://mthfr.net/methylfolate-side-effects/2012/03/01/ Best, Dr Ben
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• MTHFR at 3/8/12 7:55 AM
  • I have this condition (compound hetero) and I am learning all I can about MTHFR. I have a friend who has a single mutation (C677T) who is questioning why we all can't just take this supplement and the problems all be solved. I know that there are so many other variants to this problem.
    
    So, the question is: Can we just take this supplement and fix the main issue?
    
    Also: If we were really healthy to start with and took this supplement for the MTHFR would there still be a need to be extra careful with toxins and eating, etc. that most patients have to deal with?
    
    Maybe you can help me to explain this. Thanks!
  • If MTHFR is caught early on and did not cause any birth defects in the newborn, then living a life that is clean and healthy along with taking additional nutrients such as those in HomocysteX Plus would be sufficient for a MTHFR single mutation. However, many of us find the MTHFR later in life. This allows us to build up toxicities, have ineffective DNA methylation, weakened immune systems and all of these are harder to repair - especially with a single supplement. This is also why I recommend starting slow and working up in those with MTHFR. Fast changes may cause an unpleasant response. Everyone needs to be cautious about toxins and healthy eating - regardless of MTHFR. This is because we may have other genetic mutations which cause an inability to effectively detox - and there are many genes which control this. Best, Dr Ben
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• chondrosarcoma and MTHFR link at 3/12/12 1:18 PM
  • Do you know if there is a link between chondrosarcoma and the T/T MTHFR genotype?
  • Hello - It is likely as MTHFR defects lead to decreased methylation. Lowered methylation leads to numerous health problems and one is cancer of various forms., Chondrosarcoma is a cancer that is worsened by decreased methylation. Here is a study to support my comments: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790612/pdf/pone.0008340.pdf Best Dr Ben
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• Ringing in the ears at 3/16/12 9:44 PM
  • Hi,
    
    My husband and I both have had a lot of ringing in our ears that seems to have started in the last several months. We cannot pinpoint what the cause is, but we both started the Homocystex Plus a while back and are wondering if there could be any connection. Are there any ingredients in this that could cause this problem or has anyone else mentioned this that takes it? Thank you.
    
    
    
  • Hello - There are countless causes of tinnitus. One way to tell if HomocysteX Plus is causing tinnitus, stop using it and take some Niacin. Consider taking 1/4 tablet of Niacin twice daily for a few days and then increase to 1/2 tablet of Niacin for a few more days and then increase to 1 tablet twice daily for a week. I've searched the research for overmethylation and tinnitus - I did not find any link - however, I suspect it. Niacin by Seeking Health is here - it is time-released making it less likely to cause flushing. I also do not think it will cause much flushing if one is over-methylated. http://www.healthegoods.com/2.html Niacin is often recommended for tinnitus and has a good track record. Once the tinnitus ceases, start back on HomocysteX Plus - but take less of it. If tinnitus returns, then you need to further lower the amount of HomocysteX Plus you are taking. Keep me posted. Best Dr Ben
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• Better option? at 5/3/12 9:54 AM
  • I am not pregnant so wondering if this is the better option over Homocystex?

  • Hello - 

    HomocysteX Plus is a great formula if you have:

    - high homocysteine- tolerate methylcobalamin, methylfolate and vitamin B6 well- need additional support in producing SAMe (via TMG)

    Starting out with one capsule before breakfast is a good idea. If you feel good, then consider having another capsule of HomocysteX Plus before lunch. Do not take HomocysteX Plus after 1 pm as it may keep you awake.

    If you know you are sensitive to many nutrients and supplements, then I recommend you consider starting out with something like HomocysteX or Sublingal Active B12 with Metafolin.

    In health,Dr Ben 

     

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• Reynaud disease at 5/31/12 5:26 PM
  • I purchased this morning your homocysteine product . I JUST noticed that it is not good for people who has Reynaud disease. My farther does, that why I purchased it.
    Can you suggest something, I know niacin would be great. I will take the L methylfolate.
    I ll wait for your anwswer.
    

  • Hello - 

    I need to edit my comment about Raynaud's disease.

    HomocysteX may be useful for people with Raynaud's if they have low methylation or MTHFR defects - of the 677 variant or compound heterozygous.

    Niacin is great for Raynaud's as it increases circulation. Since Niacin is such a methyl sponge, it is a good idea to balance methylation along with HomocysteX.

    If one takes niacin long term and not any nutrients found in HomocysteX, their methylation becomes dangerously weakened setting themselves up for cancer or other serious conditions.

    Simply start with 1 capsule of HomocysteX a day at first for a few days to see how you respond - if well, you may increase to 1 capsule in the AM upon rising and another one before lunch.

    Avoiding wheat and dairy are also two good places for your father to start - defintely. Foods and healthy digestion is critical to eliminate autoimmune disease.

    In health,

    Dr Ben

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• I have Gastroparesis at 8/11/12 5:19 AM
  • Hello,
    Does HomocysteX Plus come in liquid form?
    Thank you,
    Renee

  • Hi Renee - 

    It does not come in liquid form.

    We do offer a sublingual form of methylfolate and methylcobalamin if you are interested.

    You may also open the capsule of HomcysteX Plus and mix in some juice and drink. That is totally fine.

    In health,

    Dr Lynch

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• MTHR Defect at 10/12/12 9:36 AM
  • My son, age 12, is heterozygous for both the C677T and the A1298C defects. He is taking 3mg of Metfolin per day which does seem to help, but I am not sure he is getting enough of the supporting supplements. Would HomocysteX help him, and in what dose?

  • Hello!

    Without knowing any details about your son’s labs or symptoms, please make sure he is not overmethylated.  For people who are already over methylated, HomocysteX is not for them.  A good way to see if he is over methylated is to check his histamine levels.  Low histamine = overmethylated.  If methylation is not a concern, Homocystex is a great product.  In regards to dosage, Dr. Ben recommends starting out with very small dosage and slowly---1 capsule of HomocysteX for a few days, see how your son feels and then increase from there. It is not recommended to take HomocysteX within 5 hours of going to bed as it may keep your son awake.  Eventually, 3 capsules is a pretty standard dosage of HomocysteX, but remember….increase slowly!  Example regimens for 3 capsules are:  2 capsules in the AM and 1 capsule at lunch or around 2 PM or so.  Or, 1 capsule in the AM, one at lunch and another at least 5 hours before bedtime. This way the blood levels of these critical nutrients stay where they should be and more of the nutrients are absorbed as well.

    Again, without knowing any information about your son, typically, probiotics are also a crucial component to help bind some toxins that come in through the food or drink.  I recommend your son take 1 capsule of ProBiota 12 nightly about 5-10 minutes after dinner.  If he tolerates 1 capsule, with time you may try increasing to 2 capsules.  You may likely notice improved digestion, less gas and bloating, improved immune function, improved skin health and less fatigue. http://www.healthegoods.com/probiota-12-maximum-support-50-billion-cfus-twelve-species-probiotic-60-vegetarian-capsules-seeking-health.html

    Remember, start simply and expand on your son’s regimen as long as he feels good or is noticing improvement.  If he takes too many things at once or too high a dosage and doesn’t feel so hot, you may not know what is causing it.  Also, if taking a lot of things at once, a person may feel great initially for a few weeks, but then may get not so hot feelings down the road. This requires alteration in dosages and what is being taken.  In short, introduce one new supplement at a time and start with very low dosages.   

    Health and Happiness,

    Kelly Harrington, MS, RD

    Nutritionist for Healthy Goods 

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• MTHR Defect at 10/12/12 9:36 AM
  • My son, age 12, is heterozygous for both the C677T and the A1298C defects. He is taking 3mg of Metfolin per day which does seem to help, but I am not sure he is getting enough of the supporting supplements. Would HomocysteX help him, and in what dose?

  • Hello!

    Without knowing any details about your son’s labs or symptoms, please make sure he is not overmethylated.  For people who are already over methylated, HomocysteX is not for them.  A good way to see if he is over methylated is to check his histamine levels.  Low histamine = overmethylated.  If methylation is not a concern, Homocystex is a great product.  In regards to dosage, Dr. Ben recommends starting out with very small dosage and slowly---1 capsule of HomocysteX for a few days, see how your son feels and then increase from there. It is not recommended to take HomocysteX within 5 hours of going to bed as it may keep your son awake.  Eventually, 3 capsules is a pretty standard dosage of HomocysteX, but remember….increase slowly!  Example regimens for 3 capsules are:  2 capsules in the AM and 1 capsule at lunch or around 2 PM or so.  Or, 1 capsule in the AM, one at lunch and another at least 5 hours before bedtime. This way the blood levels of these critical nutrients stay where they should be and more of the nutrients are absorbed as well.

    Again, without knowing any information about your son, typically, probiotics are also a crucial component to help bind some toxins that come in through the food or drink.  I recommend your son take 1 capsule of ProBiota 12 nightly about 5-10 minutes after dinner.  If he tolerates 1 capsule, with time you may try increasing to 2 capsules.  You may likely notice improved digestion, less gas and bloating, improved immune function, improved skin health and less fatigue. http://www.healthegoods.com/probiota-12-maximum-support-50-billion-cfus-twelve-species-probiotic-60-vegetarian-capsules-seeking-health.html

    Remember, start simply and expand on your son’s regimen as long as he feels good or is noticing improvement.  If he takes too many things at once or too high a dosage and doesn’t feel so hot, you may not know what is causing it.  Also, if taking a lot of things at once, a person may feel great initially for a few weeks, but then may get not so hot feelings down the road. This requires alteration in dosages and what is being taken.  In short, introduce one new supplement at a time and start with very low dosages.   

    Health and Happiness,

    Kelly Harrington, MS, RD

    Nutritionist for Healthy Goods 

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• Are the B vitamins in this product synthetically derived? at 10/23/12 1:00 AM
  • Are the B vitamins in this product synthetically derived or are they derived from whole food sources or plant extracts? Can you please clarify this for me with as much detail as possible.

  • Hello,

    Thank you for your inquiry. Seeking Health supplements are from the pharmaceutical industry. Synthetic vitamins are produced in laboratories from isolated chemicals that mirror their counterparts found in nature. The Seeking Health brand is not labeled natural.  Natural vitamins devived from food sources can be found on the website of livesuperfoods.com.

    http://livesuperfoods.com/search/?keywords=vitamins+B

    Have a great day :)

    Chloe

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