If you have a health condition in which estrogen levels are a factor, you may benefit from dietary compounds known as "indoles" that regulate hormone function and provide antioxidant protection. Cruciferous vegetables like kale, cabbage, and broccoli have long been associated with good health and longevity. The protective and health-promoting activity of these foods has been investigated in recent years, providing evidence of the healing properties of these vegetables.
The primary active ingredient that is present in vegetables in the Brassica family is called indole-3-carbinol, which breaks down into a number of compounds with anti-carcinogenic potential. Indole-3-carbinol has been found to have anti-angiogenic qualities in studies, meaning it inhibits the ability of tumors to expand and build new blood vessels.
Indole-3-carbinol (I3C) breaks down into a number of metabolic compounds, the most extensively researched of which is diindolylmethane (DIM). DIM in particular seems to affect how genes are expressed that regulate estrogen in the body. DIM restricts changes in estrogen-triggered genes, and therefore shows particular promise in preventing and treating cancers where estrogen is a factor, such as cervical and ovarian cancers. The estrogen-regulating properties of indoles encourages the production of 2-hydroxyestrone, a helpful and protective estrogen metabolite, in order to bring it into balance with 16-alpha hydroxy-estrone, a product of estrogen that may trigger undesirable cell changes.
Human beings today are exposed to more and more estrogen and estrogenic chemicals in the environment. Menopausal women who undergo Hormone Replacement Therapy in particular are at risk for estrogen-dependent breast cancer. Other risk factors include prolonged exposure to estrogen-like chemicals in the environment, such as BPA in hard plastics and BBP in plastic wraps and films and estrogenic foods, particularly soy.
Protect yourself with adequate dietary indole intake, from fresh, organic brassica vegetables, or by increasing your intake of these protective elements with supplementation. DIM + I3C by Seeking Health contains both indole-3-carbinol and its metabolic product, diindolylmethane, as well as other indoles for complete, well-rounded immune system support and anti-estrogenic activity.
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