BioGenesis Nutraceuticals EskaLoft 60 Capsules

ESKALOFT SUPPORT FOR A BALANCED, HEALTHY EMOTIONAL EXPRESSION*

• A blend of nutrients and amino acids to nutritionally support an enhanced mood*
• Mood modulating benefits for those with low spirits or unstable altering moods*

RHODIOLA ROSEA EXTRACT (ROOT) grows in the arctic regions of eastern Siberia. It has been used to enhance work performance, decrease physical and mental fatigue, increase stamina, and support depressed moods.* Rhodiola is considered an adaptogenic herb because of its ability to increase the body’s resistance to stress. Research shows that those who take Rhodiola experience the following: less fatigue under stress, improved exercise endurance, a decrease in inflammatory markers, such as C-Reactive protein (CRP), memory support and improved ability to learn. Other research suggests that Rhodiola also has cardioprotective, hepatoprotective, and myeloprotective effects, while also improving intracellular DNA repair mechanisms. It is currently not recommended for pregnant or nursing mothers.

ST. JOHN’S WORT EXTRACT (FLOWER)(HYPERICUM PERFORATUM) (.3%HYPERICIN, 3% HYPERFORIN) acts to enhance mood as well as itsnorepinephrine reuptake inhibition. In this way, Hypericum supports the moodregulatory effects of both serotonin and norepinephrine neurotransmittors.*

CONTRAINDICATIONS: Hypericum is generally well tolerated with less adverseeffects than conventional antidepressants. However, Hypericum is a potentinducer of the cytochrome P450 enzyme CYP3A4, which may cause potentiallyharmful interactions with pharmaceutical drugs such as serotonin antagonists,benzodiazepines, Selective Serotonin Re-uptake Inhibitors (SSRIs), Tricyclicantidepressants, calcium channel blockers, chemotherapeutic agents,contraceptive medications, and many others.

N-ACETYL L-TYROSINE (NAT) is the bioactive form ofL-Tyrosine. Tyrosine is a precursor for dopamine, norepinephrine, andepinephrine production. Tyrosine also helps support adrenal catecholamineproduction and thyroid hormone production. Many people with mood disturbancesmay have low catecholamine production.* CONTRAINDICATIONS: Tyrosine iscontraindicated in those with alkaptonuria, tyrosinemia type 1 or 2, thosetaking MAO inhibitors, pregnant women, those with hypertension, and those withmelanoma skin cancer.

DMAE (DIMETHYL AMINO ETHANOL) is a precursor to choline andmay support the production of acetylcholine in the CNS. Increased acetylcholineproduction can improve cognitive functioning and enhance mood. Research hasshown that those taking DMAE for 3 months produced significantly less theta andalpha1 brain waves. A decrease in the production of these waves has beenassociated with enhanced vigilance,improved mood, increased physical activity,and a better sense of wellbeing overall.*

5-HYDROXY L- TRYPTOPHAN (5HTP) is the immediate precursorto 5-hydroxy tryptamine (serotonin). As such, 5HTP is a useful nutritionalproduct to support healthy serotonin production.* Symptoms of serotonindeficiency may include: depression, anxiety, irritability, fears, phobias,negative thoughts, sleep problems, cravings for simple sugars and alcohol,binge eating, tension headaches, fibromyalgia, and premenstrual syndrome (PMS).CONTRAINDICATIONS: carcinoid tumors, avoid for 2 weeks after discontinuation ofMAO inhibitors, avoid during use of SSRI and tricyclic antidepressantmedications.

VITAMIN B12 (METHYLCOBALAMIN) & FOLINIC ACID (CALCIUMFOLINATE) are cofactors in the production of S-adenosylmethioe (SAMe).SAMe is a well known methyl donor that is essential for proper neurologicalfunction.* Elevated homocysteine levels are often a sign of vitamin B12 andFolate deficiency. Studies are now showing that patients with major depressionare more likely to have elevated homocysteine, low folate, particularly redcell folate, and low vitamin B12 in the blood. Supplementation with both folateand B12 have been shown to improve treatment response.* Deficiencies may leadto cognitive impairment and mood changes.*

PYRIDOXAL 5’ PHOSPHATE (COENZYME VITAMIN B6) isinvolved in the metabolism of amino acids and glycogen. It is a coenzyme in thesynthesis of nucleic acids, hemoglobin, neurotransmitters (serotonin, dopamine,norepinephrine, and gama-aminobutyric acid), and many other compounds. P5’-P is a coenzyme for over 100 enzymes, including the transaminases(some liver specific) and decarboxylases. Along with folic acid and VitaminB12, Vitamin B6 lowers homocysteine. Clinical research has shown itseffectiveness in treating depression and anxiety in women suffering fromPMS.*

L-THEANINE is a non-protein amino acid found naturally inCamillia sinensis (Green tea). L-Theanine has mood-modulating activity andmodest antioxidant activity.* Its effects on mood modulation may be throughdirect effects on GABA receptors or through effects on the metabolism andrelease of other neurotransmitters, such as dopamine.* Another benefit ofL-Theanine is its ability to enhance alpha wave activity of the brain.* Alphawaves have a mood modulating benefit while maintaining alertness. ADVERSEREACTIONS/PRECAUTIONS: There are no known adverse reactions to L-Theanine.However, due to lack of study, it is currently recommended that pregnant andnursing mothers avoid L-Theanine.

GABA (GAMMA AMINO BUTYRIC ACID) is an inhibitory amino acidthat acts directly as a neurotransmitter. GABA, like L-Theanine, hasmood-modulating activity and anti-stress benefits.*

LITHIUM is present in the human diet in ultra-trace amountsand is found in some natural mineral waters and colloidal minerals. Fish,processed meat, milk, milk products, eggs, potatoes, and vegetables are richsources of this mineral. It has been suggested that lithium, at low dosagelevels, has a generally beneficial effect on human behavior. High prescriptiondoses are often prescribed for mood stabilizing effects. CONTRAINDICATIONS:none are known for dietary

Cost Per Serving: $0.98
Additional notes: Keep tightly capped and store in a cool, dry place.
Brand: BioGenesis Nutraceuticals
SKU: BIO050
Delivery type: Vegetarian Capsule
Contraindications: Hypericum is generally well tolerated with less adverse effects than conventional antidepressants. However, Hypericum is a potent inducer of the cytochrome P450 enzyme CYP3A4, which may cause potentially harmful interactions with pharmaceutical drugs such
MPN: 282
Made In: USA
Serving size: 2 capsules
Servings per container: 30

Supplement Facts:

Ingredients
St. John's wort, 5-hydroxy-L-tryptophan, DMAE, and Rhodiola rosea

Other Ingredients
Cellulose, silica

Suggested Use
Take 2 capsules per day or as directed by a healthcare professional

Warnings
Keep out of reach of children.

Hypoallergenic: No
Does not contain: Casein, Corn, Dairy, Egg, Fish, Gluten, Peanuts, Shellfish, Soy, Tree Nuts, Wheat

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