Most of the cholesterol in the bloodstream is produced in the liver, with a smaller amount derived from the diet. Addressing cholesterol's production in the liver and its absorption in the gastrointestinal tract can be of benefit in maintaining already normal cholesterol levels.
Pharmacol-40 is derived from chitin found in crab and shrimp shells. Pharmacol-40 is a large molecule that resists digestion and is not well-absorbed into the bloodstream. Instead, remaining in the gastrointestinal tract it readily attaches to dietary cholesterol and forms an insoluble complex that is not well-absorbed.* Pharmacol-40 also can bind to the cholesterol produced in the liver and secreted in the bile, reducing its reabsorption in the intestines.
In a placebo-controlled, multicenter clinical trial, 105 subjects were randomized to receive HEP-40 (the active ingredient in Pharmacol-40) at varying amounts or placebo, and were evaluated every four weeks for 12 weeks. Significant results in maintaining optimal cholesterol levels were observed compared to placebo.* In addition, because Pharmacol-40 can bind to cholesterol in the gut, the researchers assessed whether fat-soluble vitamin absorption might also be inhibited. Vitamin D levels were tested in a random sample of 91 subjects (with 22 in the placebo group) at the beginning and end of the study, and it was determined the ingredient in Pharmacol-40 does not interfere with vitamin D absorption.
Pharmacol-40 has shown significant benefit by itself, and it can be used in conjunction with Choleast and Super EPA for optimal maintenance of already normal cholesterol levels.
Cost Per Serving: $1.45
Additional notes: Store in cool dry place.
Brand: Thorne Research
Delivery type: Vegetarian Capsule
Contraindications: There are no known adverse interactions or contraindications at publication date.
Serving size: 3 Capsules
Servings per container: 30
Hypromellose (derived from cellulose) capsule, MagnesiumCitrateLaurate.
Take 3 capsules daily with evening meal or as recommended by a health-care practitioner.
ALLERGY WARNINGS This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using this product.
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