ProBiota Immune by Seeking Health is a novel prebiotic formulation containing galactooligosaccharides and beta-glucans. These ingredients enhance natural resistance, help balance Th1/Th2 lymphocyte responses, and promote immunotolerance to environmental allergens.
Galactooligosaccharides are digestion-resistant carbohydrates that stimulate the growth of beneficial intestinal microorganisms such as Bifidobacterium and Lactobacillus.
Beta-glucans are polysaccharides that favorably modulate a variety of immune parameters.
ProBiota Immune is designed for persons who wish to beneficially modify their intestinal microflora so as to improve gastrointestinal function and optimize their immune responses. This formula can be used by children or adults and may be particularly suitable for infants, the elderly, or other persons with suboptimal immune function.
ProBiota Immune Supports:
Galactooligosaccharides (GOS) is a prebiotic naturally found in both bovine and human milk. The GOS used in ProBiota Immune are derived from cow’s milk, but the material is highly purified and completely free of dairy allergens. Prebiotic applications of GOS are of great interest because of their natural occurrence in human milk. The colonization and growth of bifidobacteria in the infant intestinal tract may in fact be attributable in large part to the presence of GOS in maternal milk.
Adding a GOS mixture to infant formula has been shown in studies to significantly boost intestinal bifidobacteria numbers while reducing levels of potential pathogens such as Clostridium, Enterobacter, Klebsiella, Pseudomonas, and Staphylococcus. In support of these findings, a double-blind, placebo-controlled study involving 206 term infants found that supplementation with 0.8g/dL of a 90% GOS mixture for 6 months increased fecal bifidobacteria levels and significantly reduced the incidence of all types of infection, including upper respiratory tract infections, infections requiring antibiotic treatment, and recurrent infections.
GOS intake can benefit adults as well as infants. In one clinical trial, as little as 2.5 g/day of GOS for 3 weeks significantly increased fecal bifidobacteria levels in a group of healthy adults while reducing the activity of bacterial enzymes that catalyzes production of potentially carcinogenic compounds in the intestinal tract.
Another group that may particularly benefit from GOS supplementation is the elderly. Aging has been associated with a pronounced decline in bifidobacterial species, increased levels of potential pathogens and putrefactive microbes, and impairments to immune function. In a double-blind, placebocontrolled, crossover trial involving 44 elderly subjects, supplementation with 5.5 g/d GOS for 10 weeks significantly increased fecal Bifidobacterium and Lactobacillus-Enterococcus populations. t.
Probiotic microorganisms also contribute to the degradation of allergy-promoting dietary antigens such as casein, and limit antigen translocation by reducing intestinal permeability. By supporting the development and maintenance of a beneficial microflora, prebiotics like GOS likewise help promote immunotolerance. Interestingly, a study showed that infants who consumed GOS experienced significant reductions in the incidence of dermatitis, recurrent wheezing, and allergic urticaria up to 18 months after the termination of the intervention period.
Beyond favorably modulating the intestinal microflora and enhancing immune function, supplementation with GOS may also improve absorption of certain dietary nutrients such as minerals.
Beta-Glucans are ubiquitous polysaccharides consisting of thousands of glucose molecules linked by combinations of bonds. Beta-glucans function mainly as structural components of the cell walls of bacteria, algae, lichens, plants, and fungi. This form of beta-glucan has been found to favorably modulate immune responses primarily by binding to cellular elements of the innate immune system such as macrophages, dendritic cells, neutrophils, and cells. These immune cells express receptors that recognize and have a binding affinity for beta-glucans.
Research in living systems finds beta-glucans effectively enhance immune function, typically without increasing production of inflammatory cytokines. Animal data show that ingestion of beta-glucans, in a sulfated or unsulfated form, facilitates a healthy immune response to a wide spectrum of pathogens such as Candida albicans, Staphylococcus aureus, E. coli, Bacillus anthracis, and influenza virus.
Beta-glucans have demonstrated immune-potentiating properties in humans. In a double-blind, placebo-controlled study, 17 patients receiving pre- and postsurgical intravenous infusions of beta-glucan experienced significantly fewer postoperative infectious complications than control patients receiving only saline. Similar results were obtained in a larger, multicenter study in which perioperative injection of beta-glucan resulted in a 39% reduction in serious infections and death in patients undergoing non-colorectal gastrointestinal surgery.
Research in both animals and humans indicates beta-glucan ingestion may also effectively mitigate allergic symptoms. Interestingly, epidemiological data show a biphasic pattern in which low exposure to beta-glucans during childhood correlates with increased risk of allergic symptoms whereas high exposure is associated with reduced risk. Clinical data clearly show supplemental beta-glucan downregulates the allergic response.
ProBiota Immune is hypoallergenic, can safely be used by children or adults and may be particularly suitable for infants, the elderly, or other persons with suboptimal immune function.
5.3 oz/ 150 g
Dr. Ben Lynch, founder and Chief Medical Officer of Seeking Health, is a naturopathic physician. While majoring in Cell and Molecular biology at the University of Washington, Dr. Ben took a trip through the South Pacific and Southeast Asia that changed his outlook on traditional medicine, and his life.
During this trip, Dr. Ben hiked through the forests, mountains and coasts of Tasmania, worked a cattle ranch in the Outback of Australia, and volunteered with Mother Theresa in Calcutta. He lived in Fiji with a family having no electricity or plumbing, experienced the Himalayan Mountains of Northern India, worked a fruit orchard in New Zealand, and returned to America with an impression of a different form of medicine than he had ever experienced with his mainstream medical education.
This profound experience led Dr. Ben to Bastyr University, and he studied the Mind-Body Connection, Environmental Medicine, Functional Medicine, and Epigenetics.
Dr. Ben saw the huge need for people to obtain foundational nutrients, and Seeking Health was born. Without foundational nutrients, biochemical dysfunction occurs and causes symptoms. Doctor after doctor and person after person do not understand the absolute requirement for our bodies to have the tools to maintain function.
“If one supports their bodily systems, especially their digestion and mental health, with pure, highly absorbable, well-formulated nutrients, the ability to remain healthy and vital significantly increases. We want your foundation rock solid and we provide the tools to do so.”
-Dr. Ben Lynch, founder of Seeking Health
Seeking Health believes that the root cause for many health conditions and supplements stem from ineffective digestion, environmental exposures, poor diet, and lack of a healthy social outlet and inlet.
Seeking Health is here to see you get better, and stay better. Their true passion is prevention.
Seeking Health is based in Bellingham, Washington and operated and managed by a team dedicated to bringing you better health through the best quality supplements, prebiotics, probiotics, and multivitamins.
Seeking Health brings you effective formulas produced without preservatives, colors, titanium dioxide, coloring, or gluten.
Cost Per Serving: $1.50
Additional notes: Free of the following common allergens: milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wehat/gluten, corn, and soybeans. Contains no artificial colors, flavors, or preservatives.
Brand: Seeking Health
Delivery type: Powder
Made In: Canada
Serving size: 5 g
Servings per container: 30
|Total Carbohydrate||5 g||2%|
|Dietary Fiber||4 g||16%|
|Prebiotic Blend||5000 mg||-|
|Galactooligosaccharides (natural, allergen-free)||-||-|
|Beta-Glucan (purified from S. cerevisiae)||-||-|
As a dietary supplement, take 1 to 2 scoops daily or as directed by a physician. Mix powder in cold, warm, or hot foods or beverages as desired.
Do not use if full-bottle shrinkwrap is broken or missing. Store in a cool, dry place (59-85 F) away from direct light. Keep out of reach of children.
ProBiota Immune is a good boost to anyone's system, but if you suffer from leaky gut as I do, then it is especially needed. (Posted on 10/17/12)