4.97 reviews

Seeking Health Active B12 Lozenge with L-5-MTHF combines potent levels of the active forms of B12 and Folate in a convenient sublingual tablet.  These B-vitamins work together to support brain and nervous system function.  They can also help protect the brain from toxins by maintaining the normal metabolism of homocycsteine, a potentially toxic amino acid metabolite that can damage the arteries.  Previously known as Sublingual Acitve B12 with Metafolin.  60 tablets

4.97 reviews
  • Seeking Health Active B12 Lozenge with L-5-MTHF

Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct

Seeking Health Active B12 Lozenge with L-5-MTHF combines potent levels of the active forms of B12 and Folate in a convenient sublingual tablet.  These B-vitamins work together to support brain and nervous system function.  They can also help protect the brain from toxins by maintaining the normal metabolism of homocycsteine, a potentially toxic amino acid metabolite that can damage the arteries.  Previously known as Sublingual Acitve B12 with Metafolin.  60 tablets

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Seeking Health Active B12 with L-F-MTHF, 60 Lozenges


Seeking Health Active B12 Lozenge with L-5-MTHF combines high-potency amounts of the active forms of vitamin B12 and Folate in one convenient tablet. 

Benefits of Active B12 Lozenges with L-5-MTHF

Vitamin B12 as methylcobalamin:

Vitamin B12 is important to the formation of healthy red blood cells, energy production, nervous system support, cognitive function, and homocysteine regulation. Although cyanocobalamin is the most commonly used form of vitamin B12 in dietary supplements, it must be converted by enzymes into an active coenzyme form to be useful. Nutritional inadequacies, enzyme defects, and tissue abnormalities can reduce the body’s ability to synthesize the active forms of B12.

In contrast, vitamin B12 as methylcobalamin is a “body-ready” form with metabolic benefits that may not be provided by other forms of vitamin B12. It appears that methylcobalamin may be particularly useful for individuals with impaired methylation capacity, including those with elevated homocysteine or neurological impairments.

Active form of folate:

This B-vitamin is important for generating red blood cells, regulating homocysteine metabolism, assisting DNA repair, and supporting neurological processes. Quatrefolic (6S) -5-metylfolate, an active form of folate, is included in this formula to help ensure more immediate effects on metabolism compared to folic acid, the form of folate commonly used in fortified foods and supplements.

Active B12 Lozenges with L-5-MTHF sublingual tablets are sweetened naturally with xylitol and are free of added flavorings. The tablets dissolve in the mouth within a few minutes or may also be swallowed whole if desired. However, this supplement may be better absorbed when slowly dissolved under the tongue rather than swallowed whole.

Newly reformulated! Now with Quatrefolic® Folate. 

Absorption of vitamin B12 is facilitated by intrinsic factor, a natural protein produced by the parietal cells of the stomach lining. B12 can also be absorbed by an alternate mechanism that does not rely on intrinsic factor when high-potency amounts of 1,000 mcg or more are taken. Active B12 Lozenges with L-5-MTHF by Seeking Health provides 1,000 mcg of vitamin B12 so that individuals without adequate intrinsic factor can enhance their intake of this essential B vitamin through oral supplementation.

Individuals who have an increased risk for vitamin B12/folate deficiency are the elderly, vegetarians, and individuals with ulcers, Crohn’s disease, bacterial overgrowth, and other gastrointestinal disorders. This dietary supplement may be useful for individuals who may have difficulty absorbing vitamin B12 and folate and are looking for a safe and efficient method to enhance their supply of these bioactive forms of nutrients.

Dietary B12 can be reliably obtained only from animal products and is a singularly difficult vitamin to absorb. Active B12 Lozenges with L-5-MTHF by Seeking Health are contained in fast-dissolving, sublingual tablets allowing quick release into the bloodstream.

Suggested Use: Take one (1) tablet daily with food

60 tablets

About Seeking Health, the company

Dr. Ben Lynch, founder and Chief Medical Officer of Seeking Health, is a naturopathic physician. While majoring in Cell and Molecular biology at the University of Washington, Dr. Ben took a trip through the South Pacific and Southeast Asia that changed his outlook on traditional medicine, and his life.

During this trip, Dr. Ben hiked through the forests, mountains and coasts of Tasmania, worked a cattle ranch in the Outback of Australia, and volunteered with Mother Theresa in Calcutta. He lived in Fiji with a family having no electricity or plumbing, experienced the Himalayan Mountains of Northern India, worked a fruit orchard in New Zealand, and returned to America with an impression of a different form of medicine than he had ever experienced with his mainstream medical education.

This profound experience led Dr. Ben to Bastyr University, and he studied the Mind-Body Connection, Environmental Medicine, Functional Medicine, and Epigenetics.

Dr. Ben saw the huge need for people to obtain foundational nutrients, and Seeking Health was born. Without foundational nutrients, biochemical dysfunction occurs and causes symptoms. Doctor after doctor and person after person do not understand the absolute requirement for our bodies to have the tools to maintain function.

  • • Without water, we die.
  • • Without food, we die.
  • • Without probiotics, we get digestive disorders.
  • • Without multivitamins, we become depressed, fatigued and sick.

“If one supports their bodily systems, especially their digestion and mental health, with pure, highly absorbable, well-formulated nutrients, the ability to remain healthy and vital significantly increases. We want your foundation rock solid and we provide the tools to do so.”

-Dr. Ben Lynch, founder of Seeking Health

Seeking Health believes that the root cause for many health conditions and supplements stem from ineffective digestion, environmental exposures, poor diet, and lack of a healthy social outlet and inlet.

  • • Once digestion is restored and optimized with the best probiotics, digestive enzymes, stomach acid and intestinal repair nutrients, one is able to absorb nutrients from foods and high quality multivitamins.
  • • Once environmental exposures are reduced, one is able to reduce toxic burden which then frees up nutrients to work in promoting health and preventing disease.
  • • Once diet is optimized, nutrients flood in, energy increases, blood sugar stabilizes and the immune system balances.
  • • Creating a social outlet and inlet allows the parasympathetic nervous system to regain control over the reactive sympathetic nervous system, allowing countless nutrients to be used proactively and in a protective manner instead of being wasted on producing stress hormones.

Seeking Health is here to see you get better, and stay better. Their true passion is prevention.

Seeking Health is based in Bellingham, Washington and operated and managed by a team dedicated to bringing you better health through the best quality supplements, prebiotics, probiotics, and multivitamins.

Seeking Health brings you effective formulas produced without preservatives, colors, titanium dioxide, coloring, or gluten.

Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct
Product Certifications:
Manufacturer: Seeking Health

Item number: SKH112

GTIN: 700580723428

Warnings: Do not use if full-bottle shrink wrap is broken or missing. Store in a cool, dry place (59-85 degrees) away from direct sunlight. Keep out of reach of children.

Package Size: 60

Serving Size: 1 lozenge

Serving Per Package: 60

Suggested Use: Take 1 lozenge daily

Refrigeration Required: No

Does Not Contain:
Tree Nuts
Supplement Facts:
Folate (as Quatrefolic® (6S)-5-Methylfolate, glucosamine salt) 800 mcg 200%
Vitamin B12 (as methylcobalamin) 1,000 mcg 16,667%
 * = Daily Value Based on a standard 2,000 calorie daily intake
** = Daily Value Not Established

Ingredients: Folate (as Quatrefolic® (6S)-5-Methylfolate, glucosamine salt); Vitamin B12 (as methylcobalamin, adeno B12)

Other Ingredients: Xylitol, silica, natural cherry flavor, ascorbyl palmitate


Share your Experience With Others!

  1. Review by Jill B.
    Posted on 3/27/2018

    Great product and service!

  2. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 5
  3. Review by Enid S.
    Posted on 4/9/2017

    Good, really good produce

  4. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 5
  5. Review by PATRICIA
    Posted on 11/21/2013

    I had been taking this product for quite a while. Blood work proved it reduced homo cysteine level. Recently I was hospitalized for an unrelated problem and was under a great deal of stress. I began to suffer from painful canker sores. Saw an otolaryngologist who prescribed mouthwash for pain but sores persisted. Research online indicated that this could be caused by a folic acid deficiency. Increased daily dose from one to two and canker sores began to improve in two days and resolved in a little over a week.

  6. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 5
  7. Review by Amber
    Posted on 11/6/2012

    I recently underwent blood work that came back showing I am compound heterozygous for the mutations C677T and A1298C. My doctor said that I should take 4mg of folic acid daily. My research has provided me with the information to know that this is not the fix and could in fact harm me. I have decided to take this supplement in lieu of cyanocobalamin and I feel great for making that decision. The pills are pleasant tasting, do not cause dry mouth and dissolve quickly. I would recommend them to anyone considering this alternate approach.

  8. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 5
  9. Review by Dave
    Posted on 10/16/2012

    First let me say that the tiny pink tablets taste wonderful and are a pleasure to let dissolve in your mouth. They are received by everyone as a treat. Kids love to hold them in their mouths.

    My family is loaded with people crippled by folate deficiency and the accompanying physical illnesses and mental stress. These vitamins have helped my family with anxiety and neurological stress. And they are probably helping us with all the physical symptoms of folate deficiency, that we have not measured, like bad cholesterol and hardening of the arteries.

    Genetic testing suggests that everyone in my family has the MTHFR C677T genes. I have two copies. I did a lot of research and thought this vitamin combination was the best on the market. I have supplied many relatives and friends with them.

    I find people in my town are very receptive to the idea that these vitamins can help them with their stress. Afterall 44% of Americans have at least one MTHFR gene for folate deficiency. Some very good reports are coming in, and I am ordering more vitamins to give away. When I buy 6 bottles, the price is very affordable and the shipping is free.

    When people's systems have no methylfolate, their neurons are not firing, and their poor bodies cannot function. The most visible symptom of folate deficiency is anxiety, which can take many forms such as stress, obsessive compulsive behavior, bipolar, depression, and twitching. Some people explode. Others withdraw. Some kill themselves.

    All of my family is deficient in serotonin. Prescriptions that boost serotonin in other people do not work for us, and some of my people get addicted to chemicals or destructive behaviors looking for relief. We have seen many early deaths, especially from those who get addicted to alcohol or prescription medication looking for relief.

    Personally, I have known extreme anxiety in my life, but in recent years changed my diet so I unknowingly got enough methylfolate to become normal. So I did not experience a great change when taking this supplement. They do not make you "high" so you cannot feel the effect. However I endured one of the most stressful months of my life, and I felt very grounded and stable. So I think the vitamins helped me. Having a steady run of happy days since taking the vitamins seems to be more than a coincidence.

    Another relative went through rough surgery, expecting to experience depression, but because of these vitamins she has felt very happy about her surgery.

    Two others who have explosive rants have been calm and happy. Another who is often depressive has felt sunshiny. One couple reports making love again.

    A relative who has had the most extreme bipolar turned to alcohol and it is killing her. The vitamins did not make any difference for her. But then alcohol destroys B vitamins.

    People in my family have some of the most famous doctors in the nation. None of them knew about the MTHFR gene nor our specific need for methylfolate. One doctor detected my Dad's B-12 deficiency, and gave him injections with the wrong kind of B-12. It did nothing to help him. I do not think they give a blood test for methyl B-12, nor an injection for it.

    Until the medical community recognizes our gene type, and the specific need for the methyl forms of these two vitamins, we need people like Dr. Ben to help us.

    I plead with people, if this gene runs in your family, give your kids this supplement. Do not wait until folate deficiency shows itself in emotional or developmental patterns that they may be crippled with for life. I am making sure all my grandkids get their daily requirement, and hope to get them all gene tested. We do not need to have another generation of suffering people.

  10. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 5
    "Great Product!"
  11. Review by Sarah
    Posted on 10/16/2012

    I purchased these because I have a difficult time swallowing pills. They dissolve quickly and taste pretty good, so I have been very happy with these tablets. Thanks.

    Order# 167016

  12. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 5
    "Great product!"
  13. Review by Kim
    Posted on 10/16/2012

    Great products and shipping. staff is friendly.

    Order # 175338

  14. Seeking Health Active B12 with L-5-MTHF Lozenges, 60 ct 4
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